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Alpha lipoic acid (ALA) is well known for its pain relieving abilities. It is known to be most effective against the burning, numbness and pain that often is associated with diabetes. This is one antioxidant, which works wonders as a pain medication.

Human clinical trials for testing the efficacy of alpha lipoic acid for pain relief have been very encouraging. In one of these trials, participants received 200 milligrams of intravenous alpha lipoic acid daily. After a period of 21 days, significant pain reduction was achieved in most participants.

Alpha lipoic acid is also responsible for rapidly and significantly reducing sensory symptoms and pain related to diabetic neuropathy. Lack of vitamin D has also been linked to pain in many studies and alpha lipoic acid being a trigger in assisting vitamin D working aids in alleviating pain. One key to the effectiveness of alpha lipoic acid in pain relief is its capability of neutralizing both water and fat-soluble free radicals. This means that alpha lipoic acid's power can be utilized in both intracellular and the extra cellular fluid to help the body rid itself of accumulated ingested toxins. Relief is a major concern for most people who suffer from chronic pain, whether it is from diabetes or other causes. Alpha lipoic acid has proved time and again to be a major relaxant and stress reliever.

Diabetics have also found alpha lipoic acid beneficial in reducing symptoms associated with nerve damage such as pain, burning, and numbness. However, supplemental alpha-lipoic acid may cause lower blood glucose levels. To avoid possible hypoglycemia, those with diabetes on anti-diabetic medication should have their blood glucose regularly monitored and anti-diabetic drug dose appropriately adjusted if required.

A note of caution: Due to lack of long-term safety data, alpha lipoic acid should be avoided by pregnant women and nursing mothers.

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